Do beta-adrenergic blocking agents increase coronary flow reserve?
نویسندگان
چکیده
منابع مشابه
The pharmacology of beta-adrenergic blocking agents.
T HE endogenously released neurotransmitter substance, norepinephrine, or an injected sympathomimetic amine, ultimately exerts its actions on an organ system by combining with an area of the effector cell termed the adrenergic “receptor site.” That drugs and neural chemical mediators react with specific receptors in living tissues was suggested by Langley”” in 1905, who suggested that effector ...
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Cardiac dysfunction in heart failure is widely recognized as a progressive process, regardless of the clinical signs and symptoms. An increase in cardiac sympathetic drive is one of the earliest neurohormonal responses occurring in patients with heart failure and may be one of the major causes of the progressive remodeling leading to the decline in myocardial function, and responsible for the p...
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The knowledge of the impact of beta-blockers on Coronary Flow Reserve (CFR) is based on experimental and clinical studies which used invasive methods (mainly Doppler Flow Wire, DFW) and non-invasive tools including scintigraphic (mainly Positron Emission Tomography, PET), magnetic resonance and Doppler ultrasound imaging. Beta-blockers have a large therapeutic indication in the treatment of cor...
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SIR,-Drs. Priscilla Kincaid-Smith and A. S. P. Hua are disturbed (24 August, p. 520) by our suggestion that beta-adrenergic blocking agents should not be used in patients with moderately severe renal failure (27 April, p. 193). They refer to a previous publication' to show that temporary deterioration in renal function in such patients may occur with the introduction of any hypotensive drug. Th...
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RECENT DEVELOPMENTS in physiological and pharmacological studies involving the autonomic nervous system have uncovered intriguing new dimensions. It appears that clinical medicine will be influenced significantly by these discoveries. Diverse pathological entities such as angina pectoris, 1-9 cardiac arrhythrnias 1,",x~ obstructive cardiomyopathies, 1~,19,2~ phaeochromocytoma, 3,21-=" and essen...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2001
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(01)01664-3